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Considered the deadliest member of the Sinestro Corps, Despotellis is a sentient biovirus capable of infecting any living organism and killing it within mere minutes. One of his most infamous massacres was when he wiped out 85% of all the planets in Sector 119, including the Reemuz, the Green Lantern of that sector, after he had wiped out Reemuz's family and homeworld.
During the Sinestro Corps initial recruitment phase, Sinestro sent Despotellis to infect and kill Maura Rayner, the mother of Kyle Rayner, knowing that the loss of another loved one would further break the "alley rat" and allow Sinestro to remove Ion from him.
During the Sinestro Corps invasion of Earth, Despotellis infected Honor Lantern Guy Gardner of Earth. Fellow Earth Lantern John Stewart took Gardner to medic Soranik Natu. Locating Despotellis inside Gardner, Natu injected him Leezle Pon, a sentient smallpox virus and sector partner of Reemuz. Leezle Pon was able to neutralize Despotellis and save Gardner's life, capturing the biovirus in the process.Intimidation: Able to infect anyone at will and kill them within minutes, Despotellis is able to "instill great fear", leading to his recruitment into the Sinestro Corps.
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